380877-02-1
380877-02-1 structure
- Name: MMV-667492
- Chemical Name: 2-(Cyclohexylamino)-3-[methyl(nitroso)amino]-1,4-naphthoquinone
- CAS Number: 380877-02-1
- Molecular Formula: C17H19N3O3
- Molecular Weight: 313.351
- Create Date: 2020-01-12 09:41:50
- Modify Date: 2025-09-18 10:22:08
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MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM; exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787; a novel antimetastatic agent for the treatment of metastatic osteosarcoma.
| Name | 2-(Cyclohexylamino)-3-[methyl(nitroso)amino]-1,4-naphthoquinone |
|---|---|
| Synonyms |
1,4-Naphthalenedione, 2-(cyclohexylamino)-3-(methylnitrosoamino)-
2-(Cyclohexylamino)-3-[methyl(nitroso)amino]-1,4-naphthoquinone |
| Description | MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM; exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787; a novel antimetastatic agent for the treatment of metastatic osteosarcoma. |
|---|---|
| References | References 1. Çelik H, et al. Mol Cancer Ther. 2015 Nov;14(11):2497-507. View Related Products by Target Ezrin |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 486.5±45.0 °C at 760 mmHg |
| Molecular Formula | C17H19N3O3 |
| Molecular Weight | 313.351 |
| Flash Point | 248.0±28.7 °C |
| Exact Mass | 313.142639 |
| LogP | 2.80 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.661 |