camp sodium salt

Modify Date: 2024-01-03 09:43:24

camp sodium salt Structure
camp sodium salt structure
Common Name camp sodium salt
CAS Number 37839-81-9 Molecular Weight 351.19
Density N/A Boiling Point 701.5ºC at 760 mmHg
Molecular Formula C10H11N5NaO6P Melting Point 219 - 220ºC
MSDS N/A Flash Point 378ºC

 Use of camp sodium salt


Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes[1][2][3].

 Names

Name 3',5'-cAMP Na Hydrate
Synonym More Synonyms

 camp sodium salt Biological Activity

Description Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes[1][2][3].
Related Catalog
Target

Human Endogenous Metabolite

Microbial Metabolite

In Vitro Cyclic AMP (Cyclic adenosine monophosphate) sodium modulates mediator generation. Cyclic AMP sodium suppresses the expression of pro-inflammatory cytokines, including TNF-α and IL-12, and enhances the production of the anti-inflammatory cytokine IL-10.
References

[1]. G M Fimia, et al. Cyclic AMP signaling. J Cell Sci. 2001 Jun;114(Pt 11):1971-2.  

[2]. Paolo Sassone-Corsi, et al. The cyclic AMP pathway. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148.  

[3]. Aronoff DM, et, al. Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. J Interferon Cytokine Res. 2006 Nov;26(11):827-33.  

 Chemical & Physical Properties

Boiling Point 701.5ºC at 760 mmHg
Melting Point 219 - 220ºC
Molecular Formula C10H11N5NaO6P
Molecular Weight 351.19
Flash Point 378ºC
Exact Mass 351.034454
PSA 167.48000
LogP 0.20200
Storage condition −20°C
Water Solubility H2O: 50 mg/mL | Soluble in water (50 mg/ml).

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7357900
CHEMICAL NAME :
Adenosine, cyclic 3',5'-(hydrogen phosphate)-, monosodium salt
CAS REGISTRY NUMBER :
37839-81-9
LAST UPDATED :
199409
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H11-N5-O6-P.Na

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14300 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes
REFERENCE :
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 1(2),15,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
395 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor Behavioral - ataxia
REFERENCE :
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 1(2),15,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
645 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor Behavioral - ataxia
REFERENCE :
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 1(2),15,1976

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS AU7357900
HS Code 29349990

 Precursor & DownStream

Precursor  0

DownStream  1

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 Synonyms

4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, sodium salt, (4aR,6R,7R,7aS)- (1:1)
Adenosine 3',5'-cyclic monophosphate sodium salt monohydrate
3’,5‘-Cyclic AMP sodium salt
Adenosine 3',5'-Cyclic Monophosphate Sodium Salt Hydrate
Sodium (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide
3',5'-Cyclic AMP Sodium Salt Hydrate
Adenosine 3’,5‘-cyclic monophosphate sodium salt monohydrate
MFCD00069736
CAMP SODIUM SALT
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