N,N-Diethylhydroxylamine

Modify Date: 2025-08-20 15:25:44

N,N-Diethylhydroxylamine Structure
N,N-Diethylhydroxylamine structure
 Common Name N,N-Diethylhydroxylamine
CAS Number 3710-84-7 Molecular Weight 89.136
Density 0.9±0.1 g/cm3 Boiling Point 133.0±0.0 °C at 760 mmHg
Molecular Formula C4H11NO Melting Point −26-−25 °C(lit.)
MSDS Chinese USA Flash Point 45.0±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07		 Signal Word Warning

 Names

Name N,N-Diethylhydroxylamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 133.0±0.0 °C at 760 mmHg
Melting Point −26-−25 °C(lit.)
Molecular Formula C4H11NO
Molecular Weight 89.136
Flash Point 45.0±0.0 °C
Exact Mass 89.084061
PSA 23.47000
LogP -0.09
Vapour density 3.07 (vs air)
Vapour Pressure 5.2±0.4 mmHg at 25°C
Index of Refraction 1.433
Storage condition Flammables area
Stability Stable. Hygroscopic. Flammable. Incompatible with strong oxidizing agents, strong acids.
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NC3500000
CHEMICAL NAME :
Hydroxylamine, N,N-diethyl-
CAS REGISTRY NUMBER :
3710-84-7
BEILSTEIN REFERENCE NO. :
1731349
LAST UPDATED :
199712
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C4-H11-N-O
MOLECULAR WEIGHT :
89.16
WISWESSER LINE NOTATION :
QN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD80 - Lethal Dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
100 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
180 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
18 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
180 mg/kg
REFERENCE :
CAES** Reports Supported by the Pennwalt Corp. and the Center for Air Environment Studies at the Pennsylvania State University Volume(issue)/page/year: 492-78,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83719 No. of Facilities: 62 (estimated) No. of Industries: 1 No. of Occupations: 10 No. of Employees: 6533 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83719 No. of Facilities: 162 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 950 (estimated) No. of Female Employees: 14 (estimated)

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H312 + H332-H315-H319
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R10;R20/21;R36/37/38;R40
Safety Phrases S36/37-S45-S36/37/39-S26-S16
RIDADR UN 1993 3/PG 3
WGK Germany 1
RTECS NC3500000
Packaging Group III
Hazard Class 3
HS Code 2928000090

 Synthetic Route

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles17

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Hydrogen abstraction ability of different aromatic nitroxides.

Free Radic. Res. 38(1) , 67-72, (2004)

Indolinonic aromatic nitroxides have been shown to efficiently inhibit free radical mediated oxidation reactions in biological systems. Since all antioxidants also possess pro-oxidant activity, possib...

The effect of diethylhydroxylamine on the incidence of tumors induced by benzo(a)pyrene in the mouse.

Drug Chem. Toxicol. 7(4) , 315-27, (1984)

Groups of 20 male and 20 female CD-1(ICR)Br mice were treated either with 0, 3, 30, or 300 mg diethylhydroxylamine (DEHA)/kg-day (administered via the drinking water) from 57-112 days of age. For the ...

N,N-diethylhydroxylamine: a new electron donor to photosystem II.

Biochem. Biophys. Res. Commun. 179(2) , 1127-33, (1991)

Diethylhydroxylamine, when added to beet spinach thylakoid membranes in the reaction mixture enhanced both photosystem II mediated dichlorophenolindophenol photoreduction and whole chain electron tran...

 Synonyms

N,N-Diethylhydroxylamine
pennstop,anhydrous
DEHA
pennstop
DIETHYL HYDROXYLAMINE
N-Hydroxydiethylamine
N-DiethylhydroxylaMine
[Ethyl(hydroxy)amino]ethan
ethylhydroxyethylamine
N-Ethyl-N-hydroxyethanamine
N,N-Diethylhydroxyla
Ethanamine, N-ethyl-N-hydroxy-
Diethylhydroxyamine
MFCD00002126
N,N-diethyl-hydroxylamine
N-ethyl-N-hydroxyethylamine
Pennstop 1866
EINECS 223-055-4
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