N,N-Diethylhydroxylamine
Names
[ CAS No. ]:
3710-84-7
[ Name ]:
N,N-Diethylhydroxylamine
[Synonym ]:
N,N-Diethylhydroxylamine
pennstop,anhydrous
DEHA
pennstop
DIETHYL HYDROXYLAMINE
N-Hydroxydiethylamine
N-DiethylhydroxylaMine
[Ethyl(hydroxy)amino]ethan
ethylhydroxyethylamine
N-Ethyl-N-hydroxyethanamine
N,N-Diethylhydroxyla
Ethanamine, N-ethyl-N-hydroxy-
Diethylhydroxyamine
MFCD00002126
N,N-diethyl-hydroxylamine
N-ethyl-N-hydroxyethylamine
Pennstop 1866
EINECS 223-055-4
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
133.0±0.0 °C at 760 mmHg
[ Melting Point ]:
−26-−25 °C(lit.)
[ Molecular Formula ]:
C4H11NO
[ Molecular Weight ]:
89.136
[ Flash Point ]:
45.0±0.0 °C
[ Exact Mass ]:
89.084061
[ PSA ]:
23.47000
[ LogP ]:
-0.09
[ Vapour density ]:
3.07 (vs air)
[ Vapour Pressure ]:
5.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.433
[ Storage condition ]:
Flammables area
[ Stability ]:
Stable. Hygroscopic. Flammable. Incompatible with strong oxidizing agents, strong acids.
[ Water Solubility ]:
soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NC3500000
- CHEMICAL NAME :
- Hydroxylamine, N,N-diethyl-
- CAS REGISTRY NUMBER :
- 3710-84-7
- BEILSTEIN REFERENCE NO. :
- 1731349
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 18
- MOLECULAR FORMULA :
- C4-H11-N-O
- MOLECULAR WEIGHT :
- 89.16
- WISWESSER LINE NOTATION :
- QN2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD80 - Lethal Dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 100 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 180 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 18 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 180 mg/kg
- REFERENCE :
- CAES** Reports Supported by the Pennwalt Corp. and the Center for Air Environment Studies at the Pennsylvania State University Volume(issue)/page/year: 492-78,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83719 No. of Facilities: 62 (estimated) No. of Industries: 1 No. of Occupations: 10 No. of Employees: 6533 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83719 No. of Facilities: 162 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 950 (estimated) No. of Female Employees: 14 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H312 + H332-H315-H319
[ Precautionary Statements ]:
P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R10;R20/21;R36/37/38;R40
[ Safety Phrases ]:
S36/37-S45-S36/37/39-S26-S16
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
NC3500000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2928000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2928000090
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
Free Radic. Res. 38(1) , 67-72, (2004)
Indolinonic aromatic nitroxides have been shown to efficiently inhibit free radical mediated oxidation reactions in biological systems. Since all antioxidants also possess pro-oxidant activity, possib...
The effect of diethylhydroxylamine on the incidence of tumors induced by benzo(a)pyrene in the mouse.Drug Chem. Toxicol. 7(4) , 315-27, (1984)
Groups of 20 male and 20 female CD-1(ICR)Br mice were treated either with 0, 3, 30, or 300 mg diethylhydroxylamine (DEHA)/kg-day (administered via the drinking water) from 57-112 days of age. For the ...
N,N-diethylhydroxylamine: a new electron donor to photosystem II.Biochem. Biophys. Res. Commun. 179(2) , 1127-33, (1991)
Diethylhydroxylamine, when added to beet spinach thylakoid membranes in the reaction mixture enhanced both photosystem II mediated dichlorophenolindophenol photoreduction and whole chain electron tran...