4-Methylhistamine dihydrochloride

Modify Date: 2024-01-03 08:38:13

4-Methylhistamine dihydrochloride structure	Common Name	4-Methylhistamine dihydrochloride
	CAS Number	36376-47-3	Molecular Weight	198.09400
	Density	1.1g/cm3	Boiling Point	345ºC at 760 mmHg
	Molecular Formula	C₆H₁₃Cl₂N₃	Melting Point	N/A
	MSDS	N/A	Flash Point	189.3ºC

Use of 4-Methylhistamine dihydrochloride

4-Methylhistamine (dihydrochloride) is the potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine (dihydrochloride) has the potential for the research of immune-related diseases such as cancer and autoimmune disorders[1].

Name	2-(5-methyl-1H-imidazol-4-yl)ethanamine,dihydrochloride
Synonym	More Synonyms

Description	4-Methylhistamine (dihydrochloride) is the potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine (dihydrochloride) has the potential for the research of immune-related diseases such as cancer and autoimmune disorders[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	histamine 4 receptor[1]
References	[1]. Ahmad SF, et al. Stimulation of the histamine 4 receptor with 4-methylhistamine modulates the effects of chronic stress on the Th1/Th2 cytokine balance. Immunobiology. 2015;220(3):341-349.

Density	1.1g/cm3
Boiling Point	345ºC at 760 mmHg
Molecular Formula	C₆H₁₃Cl₂N₃
Molecular Weight	198.09400
Flash Point	189.3ºC
Exact Mass	197.04900
PSA	54.70000
LogP	2.52360
Index of Refraction	1.558
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI3505800

CHEMICAL NAME :: Imidazole, 4-(2-aminoethyl)-5-methyl-, dihydrochloride

CAS REGISTRY NUMBER :: 36376-47-3

LAST UPDATED :: 199206

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H11-N3.2Cl-H

MOLECULAR WEIGHT :: 198.12

WISWESSER LINE NOTATION :: T5M CNJ D2Z E1 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 991 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - pleural effusion

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 77,54,1943

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 198 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 77,54,1943

Hazard Codes	Xi
HS Code	2933290090

2-[5-methyl-1-(...

CAS#:120231-08-5

~86%

4-Methylhistami...

CAS#:36376-47-3

Literature: Davey, D. D.; Lumma, W. C. Journal of Organic Chemistry, 1989 , vol. 54, # 13 p. 3211 - 3213

5-methyl-1-(phe...

CAS#:75815-57-5

4-Methylhistami...

CAS#:36376-47-3

Literature: Journal of Organic Chemistry, , vol. 54, # 13 p. 3211 - 3213

nona-2,6-dienal...

CAS#:75815-55-3

4-Methylhistami...

CAS#:36376-47-3

Literature: Journal of Organic Chemistry, , vol. 54, # 13 p. 3211 - 3213

ethyl 1-benzyl-...

CAS#:75815-53-1

4-Methylhistami...

CAS#:36376-47-3

Literature: Journal of Organic Chemistry, , vol. 54, # 13 p. 3211 - 3213

2-[5-methyl-1-(...

CAS#:120231-07-4

4-Methylhistami...

CAS#:36376-47-3

Literature: Journal of Organic Chemistry, , vol. 54, # 13 p. 3211 - 3213

2-[5-methyl-1-(...

CAS#:120231-06-3

4-Methylhistami...

CAS#:36376-47-3

Literature: Journal of Organic Chemistry, , vol. 54, # 13 p. 3211 - 3213

Precursor 6
CAS#:120231-08-5 2-[5-methyl-1-(... CAS#:75815-57-5 5-methyl-1-(phe... CAS#:75815-55-3 nona-2,6-dienal... CAS#:75815-53-1 ethyl 1-benzyl-...
CAS#:120231-07-4 2-[5-methyl-1-(... CAS#:120231-06-3 2-[5-methyl-1-(...
DownStream 0

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-<5-methyl-1H-imidazol-4-yl>ethanamine dihydrochloride

5-metilistamina diclorinato

5-Methylhistamine dihydrochloride

5-Methyl-1H-imidazole-4-ethanamine dihydrochloride

2-methylhistamine dihydrochloride

5-metilistamina dicloridrato

4-Methylhistamine dihydrochloride

DC Chemicals Limited
China
Product Name: 4-Methylhistamine dihydrochloride
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-Methylhistamine dihydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

4-Methylhistamine dihydrochloride suppliers

Price: ￥1768/250mg

Reference only. check more 4-Methylhistamine dihydrochloride price

4-Methylhistamine dihydrochloride

Use of 4-Methylhistamine dihydrochloride

Names