1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione
Modify Date: 2024-01-08 17:23:44
![1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione Structure](https://www.chemsrc.com/caspic/093/35959-38-7.png)
1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione structure
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Common Name | 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione | ||
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| CAS Number | 35959-38-7 | Molecular Weight | 227.22 | |
| Density | 1.466g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H13N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione5′-Amino-2′,5′-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione |
|---|---|
| Synonym | More Synonyms |
| Description | 5′-Amino-2′,5′-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 1.466g/cm3 |
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| Molecular Formula | C9H13N3O4 |
| Molecular Weight | 227.22 |
| Exact Mass | 227.09100 |
| PSA | 110.34000 |
| Index of Refraction | 1.601 |
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~96%
1-[(2R,4S,5R)-5... CAS#:35959-38-7 |
| Literature: Ruda, Gian Filippo; Nguyen, Corinne; Ziemkowski, Przemyslaw; Felczak, Krzysztof; Kasinathan, Ganasan; Musso-Buendia, Alexander; Sund, Christian; Zhou, Xiao Xiong; Kaiser, Marcel; Ruiz-Perez, Luis M.; Brun, Reto; Kulikowski, Tadeusz; Johansson, Nils Gunnar; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H. ChemMedChem, 2011 , vol. 6, # 2 p. 309 - 320 |
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~%
1-[(2R,4S,5R)-5... CAS#:35959-38-7 |
| Literature: Chi, Xiuling; Pahari, Pallab; Nonaka, Koichi; Van Lanen, Steven G. Journal of the American Chemical Society, 2011 , vol. 133, # 36 p. 14452 - 14459 |
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~%
1-[(2R,4S,5R)-5... CAS#:35959-38-7 |
| Literature: Ruda, Gian Filippo; Nguyen, Corinne; Ziemkowski, Przemyslaw; Felczak, Krzysztof; Kasinathan, Ganasan; Musso-Buendia, Alexander; Sund, Christian; Zhou, Xiao Xiong; Kaiser, Marcel; Ruiz-Perez, Luis M.; Brun, Reto; Kulikowski, Tadeusz; Johansson, Nils Gunnar; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H. ChemMedChem, 2011 , vol. 6, # 2 p. 309 - 320 |
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~%
1-[(2R,4S,5R)-5... CAS#:35959-38-7 |
| Literature: Research Corporation Patent: US4000260 A1, 1976 ; |
![2-bromo-N-[[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl]acetamide structure](https://www.chemsrc.com/caspic/345/106929-03-7.png)
CAS#:106929-03-7
CAS#:66-22-8
CAS#:58-98-0| 5'-Amino-2',5'-dideoxyuridin |
| 5'-Amino-2'-deoxyuridine |
| 5'-NH2-2'-dU |
| Uridine,5'-amino-2',5'-dideoxy |
| 5'-amino-2',5'-dideoxyuridine |