![1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione结构式](https://www.chemsrc.com/caspic/093/35959-38-7.png)
1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione结构式
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常用名 | 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione | 英文名 | 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione |
|---|---|---|---|---|
| CAS号 | 35959-38-7 | 分子量 | 227.22 | |
| 密度 | 1.466g/cm3 | 沸点 | N/A | |
| 分子式 | C9H13N3O4 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
用途5′-氨基-2′,5′-二脱氧尿苷是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。 |
| 英文名 | 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione |
|---|---|
| 英文别名 | 更多 |
| 描述 | 5′-氨基-2′,5′-二脱氧尿苷是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。 |
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| 相关类别 | |
| 参考文献 |
| 密度 | 1.466g/cm3 |
|---|---|
| 分子式 | C9H13N3O4 |
| 分子量 | 227.22 |
| 精确质量 | 227.09100 |
| PSA | 110.34000 |
| 折射率 | 1.601 |
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~96%
1-[(2R,4S,5R)-5... 35959-38-7 |
| 文献：Ruda, Gian Filippo; Nguyen, Corinne; Ziemkowski, Przemyslaw; Felczak, Krzysztof; Kasinathan, Ganasan; Musso-Buendia, Alexander; Sund, Christian; Zhou, Xiao Xiong; Kaiser, Marcel; Ruiz-Perez, Luis M.; Brun, Reto; Kulikowski, Tadeusz; Johansson, Nils Gunnar; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H. ChemMedChem, 2011 , vol. 6, # 2 p. 309 - 320 |
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~%
1-[(2R,4S,5R)-5... 35959-38-7 |
| 文献：Chi, Xiuling; Pahari, Pallab; Nonaka, Koichi; Van Lanen, Steven G. Journal of the American Chemical Society, 2011 , vol. 133, # 36 p. 14452 - 14459 |
|
~%
1-[(2R,4S,5R)-5... 35959-38-7 |
| 文献：Ruda, Gian Filippo; Nguyen, Corinne; Ziemkowski, Przemyslaw; Felczak, Krzysztof; Kasinathan, Ganasan; Musso-Buendia, Alexander; Sund, Christian; Zhou, Xiao Xiong; Kaiser, Marcel; Ruiz-Perez, Luis M.; Brun, Reto; Kulikowski, Tadeusz; Johansson, Nils Gunnar; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H. ChemMedChem, 2011 , vol. 6, # 2 p. 309 - 320 |
|
~%
1-[(2R,4S,5R)-5... 35959-38-7 |
| 文献：Research Corporation Patent: US4000260 A1, 1976 ; |
| 5'-Amino-2',5'-dideoxyuridin |
| 5'-Amino-2'-deoxyuridine |
| 5'-NH2-2'-dU |
| Uridine,5'-amino-2',5'-dideoxy |
| 5'-amino-2',5'-dideoxyuridine |
![2-bromo-N-[[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl]acetamide结构式](https://www.chemsrc.com/caspic/345/106929-03-7.png)
CAS号106929-03-7
CAS号66-22-8
CAS号58-98-0