2-Oleoylglycerol
2-Oleoylglycerol structure
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Common Name | 2-Oleoylglycerol | ||
|---|---|---|---|---|
| CAS Number | 3443-84-3 | Molecular Weight | 356.54000 | |
| Density | 0.969 g/cm3 | Boiling Point | 485.4ºC at 760mmHg | |
| Molecular Formula | C21H40O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 113ºC | |
Use of 2-Oleoylglycerol2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo[1][2]. |
| Name | 2-oleoylglycerol |
|---|---|
| Synonym | More Synonyms |
| Description | 2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo[1][2]. |
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| Related Catalog | |
| Target |
IC50: 2.5 μM (hGPR119) (in COS-7 cells)[1] |
| References |
| Density | 0.969 g/cm3 |
|---|---|
| Boiling Point | 485.4ºC at 760mmHg |
| Molecular Formula | C21H40O4 |
| Molecular Weight | 356.54000 |
| Flash Point | 113ºC |
| Exact Mass | 356.29300 |
| PSA | 66.76000 |
| LogP | 4.92030 |
| Index of Refraction | 1.478 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| Precursor 9 | |
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| DownStream 4 | |
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Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol.
J. Physiol. 593(8) , 2097-109, (2015) Sensing of dietary triacylglycerol in the proximal small intestine results in physiological, hormonal and behavioural responses. However, the exact physiological pathways linking intestinal fat sensin... |
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TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.
Am. J. Physiol. Lung Cell. Mol. Physiol. 307(2) , L158-72, (2014) The treatment of acute lung injury caused by exposure to reactive chemicals remains challenging because of the lack of mechanism-based therapeutic approaches. Recent studies have shown that transient ... |
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Identification of 2-[2-(4-tert-butylphenyl)ethyl]-N-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide (29) as an orally available MGAT2 inhibitor.
Bioorg. Med. Chem. 23 , 5922-31, (2015) MGAT2 (monoacylglycerol acyltransferase 2) is expected to be an attractive target for the drug treatment of obesity, diabetes, and other disease. We describe our exploration and structure-activity rel... |
| glycerine monooleate |
| 2-o-Kresyloxy-glutarsaeure-diethylester |
| 2-MONOOLEIN |
| 1,3-dihydroxypropan-2-yl oleate |
| 2-monooleoylglycerol |
| 2-Oleoylglycerol |
| glycerin oleate |