iMAC2

Modify Date: 2024-01-06 18:36:56

iMAC2 structure	Common Name	iMAC2
	CAS Number	335166-36-4	Molecular Weight	469.19
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₀Br₂FN₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of iMAC2

iMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release[1].

Name	3,6-Dibromo-9-[2-fluoro-3-(1-piperazinyl)propyl]-9H-carbazole dih ydrochloride

Description	iMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Others Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 28 nM (MAC)[1]
References	[1]. Peixoto PM, et al. MAC inhibitors suppress mitochondrial apoptosis. Biochem J. 2009 Oct 12;423(3):381-7.

Molecular Formula	C₁₉H₂₀Br₂FN₃
Molecular Weight	469.19
Exact Mass	538.95400
PSA	20.20000
LogP	6.43350