335166-36-4

335166-36-4 structure

Name: iMAC2
Chemical Name: 3,6-Dibromo-9-[2-fluoro-3-(1-piperazinyl)propyl]-9H-carbazole dih ydrochloride
CAS Number: 335166-36-4
Molecular Formula: C₁₉H₂₀Br₂FN₃
Molecular Weight: 469.19
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-05-31 21:30:32
Modify Date: 2024-01-06 18:36:56
iMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release[1].

Name	3,6-Dibromo-9-[2-fluoro-3-(1-piperazinyl)propyl]-9H-carbazole dih ydrochloride

Description	iMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Others Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 28 nM (MAC)[1]
References	[1]. Peixoto PM, et al. MAC inhibitors suppress mitochondrial apoptosis. Biochem J. 2009 Oct 12;423(3):381-7.