iMAC2

Names

[ CAS No. ]:
335166-36-4

[ Name ]:
iMAC2

Biological Activity

[Description]:

iMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Others
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: 28 nM (MAC)[1]


[References]

[1]. Peixoto PM, et al. MAC inhibitors suppress mitochondrial apoptosis. Biochem J. 2009 Oct 12;423(3):381-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H20Br2FN3

[ Molecular Weight ]:
469.19

[ Exact Mass ]:
538.95400

[ PSA ]:
20.20000

[ LogP ]:
6.43350

Related Compounds