BPDBA

Modify Date: 2025-09-27 17:19:59

BPDBA Structure
BPDBA structure
Common Name BPDBA
CAS Number 312281-74-6 Molecular Weight 363.28
Density N/A Boiling Point N/A
Molecular Formula C19H20Cl2N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BPDBA


BPDBA is a selective and noncompetitive betaine/GABA transporter (BGT-1) inhibitor with IC50s of 20 μM and 35 μM against human BGT-1 and mouse GAT2, respectively[1].

 Names

Name BPDBA
Synonym More Synonyms

 BPDBA Biological Activity

Description BPDBA is a selective and noncompetitive betaine/GABA transporter (BGT-1) inhibitor with IC50s of 20 μM and 35 μM against human BGT-1 and mouse GAT2, respectively[1].
Related Catalog
In Vivo BPDBA 被预测具有良好的口服吸收和血脑屏障穿透性能[1]。
References

[1]. Kragholm B, et al. Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile. Biochem Pharmacol. 2013 Aug 15;86(4):521-8.  

 Chemical & Physical Properties

Molecular Formula C19H20Cl2N2O
Molecular Weight 363.28
InChIKey OIDACLQVAGIDMT-UHFFFAOYSA-N
SMILES O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1Cl
Storage condition -20°C

 Synonyms

N-(1-benzylpiperidin-4-yl)-2,4-dichlorobenzamide
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