spermine tetrahydrochloride

Modify Date: 2025-08-25 20:11:19

spermine tetrahydrochloride Structure
spermine tetrahydrochloride structure
Common Name spermine tetrahydrochloride
CAS Number 306-67-2 Molecular Weight 334.157
Density 1.01 g/mL at 20 °C Boiling Point 308.4ºC at 760mmHg
Molecular Formula C10H30Cl4N4 Melting Point 310-311 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 175.6ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of spermine tetrahydrochloride


Spermine, a polycationic biogenic polyamine derived from spermidine, may be used in a wide variety of biological applications as a supplement or regulatory agent.Used as co-matrix with DHB for MALDI-MS of sialylated glycans in negative ion mode.

 Names

Name N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.01 g/mL at 20 °C
Boiling Point 308.4ºC at 760mmHg
Melting Point 310-311 °C (dec.)(lit.)
Molecular Formula C10H30Cl4N4
Molecular Weight 334.157
Flash Point 175.6ºC
Exact Mass 332.106812
PSA 76.10000
LogP 5.03380
Appearance of Characters powder
Storage condition 2-8°C
Water Solubility H2O: 1 M at 20 °C, clear, colorless

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EJ7230000
CHEMICAL NAME :
1,4-Butanediamine, N,N'-bis(3-aminopropyl)-, tetrahydrochloride
CAS REGISTRY NUMBER :
306-67-2
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C10-H26-N4.4Cl-H
MOLECULAR WEIGHT :
348.24
WISWESSER LINE NOTATION :
Z3M4M3Z 4GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
370 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
16700 nmol/L
REFERENCE :
BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 5,227,1967

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS EJ7230000
HS Code 2921290000

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2921290000
Summary 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles22

More Articles
Interaction of myo-inositol hexakisphosphate with biogenic and synthetic polyamines.

Org. Biomol. Chem. 13 , 7500-12, (2015)

Within all the eukaryotic cells myo-inositol phosphates (InsPs) are an important group of biomolecules that are potentially related to signaling functions. The most abundant member of this family in n...

An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution.

Anal. Sci. 31 , 721-4, (2015)

This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a laye...

Effect of Novel Starter Culture on Reduction of Biogenic Amines, Quality Improvement, and Sensory Properties of Doenjang, a Traditional Korean Soybean Fermented Sauce Variety.

J. Food Sci. 80 , M1794-803, (2015)

To select appropriate microorganisms as starter cultures for the reliable and reproducible fermentation of soybean fermented products of Korean Doenjang, various ratios of fungi (Aspergillus oryzae J,...

 Synonyms

N,N'-Bis(3-aMinopropyl)-1,4-butanediaMine Tetrahydrochloride
EINECS 206-189-8
N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride
Spermine tetrahydrochloride
N-(2-Aminoethyl)-N'-(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
1,5,10,14-tetraazoniatetradecane tetrachloride
Additive Screening
Spermine hydrochloride
Geontine Tetrahydrochloride
Spermine tetrahydrochloride 0.1 M
1,4-Butanediamine, N-(2-aminoethyl)-N-(3-aminopropyl)-, hydrochloride (1:4)
Musculamine tetrahydrochloride
MFCD00012914
Neuridine tetrahydrochloride
Spm tetrahydrochloride
Gerontine tetrahydrochloride
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