MRGPRX1 agonist 2

Modify Date: 2025-08-27 11:40:40

MRGPRX1 agonist 2 structure	Common Name	MRGPRX1 agonist 2
	CAS Number	302952-43-8	Molecular Weight	270.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₄N₂OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MRGPRX1 agonist 2

MRGPRX1 agonist 2 (compound 1a) is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.48 μM. MRGPRX1 agonist 2 can be used for researching neuropathic pain[1].

Name	MRGPRX1 agonist 2

Description	MRGPRX1 agonist 2 (compound 1a) is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.48 μM. MRGPRX1 agonist 2 can be used for researching neuropathic pain[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	EC50: 0.48 μM (MRGPRX1)[1]
References	[1]. Berhane I, et al. Thieno[2,3-d]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1). J Med Chem. 2022;65(4):3218-3228.

Molecular Formula	C₁₅H₁₄N₂OS
Molecular Weight	270.35
InChIKey	QBBAZGZWTDSFJF-UHFFFAOYSA-N
SMILES	Cc1ccccc1Oc1ncnc2sc(C)c(C)c12

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MRGPRX1 agonist 2

Use of MRGPRX1 agonist 2

Names

MRGPRX1 agonist 2 Biological Activity

Chemical & Physical Properties

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