2169273-66-7

2169273-66-7 structure
2169273-66-7 structure
  • Name: EphA2 agonist 2
  • Chemical Name: EphA2 agonist 2
  • CAS Number: 2169273-66-7
  • Molecular Formula: C40H56N10O6
  • Molecular Weight: 772.94
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Ephrin Receptor
  • Create Date: 2022-07-02 02:29:50
  • Modify Date: 2024-01-10 12:29:56
  • EphA2 agonist 2 (Lead compound) is a selective EphA2 agonist with antitumor activities. EphA2 agonist 2 can cross the BBB[1].

Name EphA2 agonist 2
Description EphA2 agonist 2 (Lead compound) is a selective EphA2 agonist with antitumor activities. EphA2 agonist 2 can cross the BBB[1].
Related Catalog
In Vitro EphA2 agonist 2 (Lead compound) shows antiproliferation activity with IC50 values of 2.1 ± 1.05 μM and 5.2 ± 2.56 μM against U251 EphA2 overexpressed and U251 wild type cells, respectively[1].
References

[1]. Orahoske CM, et al. Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth. Bioorg Med Chem. 2020 Sep 15;28(18):115656.

Molecular Formula C40H56N10O6
Molecular Weight 772.94