2377379-39-8

2377379-39-8 structure

Name: MRGPRX1 agonist 1
Chemical Name: MRGPRX1 agonist 1
CAS Number: 2377379-39-8
Molecular Formula: C₂₃H₂₁N₃O₄S
Molecular Weight: 435.50
Catalog: Signaling Pathways Others Others
Create Date: 2019-12-08 18:58:19
Modify Date: 2024-04-05 13:58:09
MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].

Name	MRGPRX1 agonist 1

Description	MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].
Related Catalog	Signaling Pathways >> Others >> Others
Target	EC50: 50 nM (MRGPRX1)[1]
References	[1]. Prchalová E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641.