Ingenol

Modify Date: 2024-01-02 07:17:37

Ingenol structure	Common Name	Ingenol
	CAS Number	30220-46-3	Molecular Weight	348.433
	Density	1.3±0.1 g/cm3	Boiling Point	523.8±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₈O₅	Melting Point	153 °C
	MSDS	N/A	Flash Point	284.7±26.6 °C

Use of Ingenol

Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.

Name	ingenol
Synonym	More Synonyms

Description	Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
Related Catalog	Natural Products >> Terpenoids and Glycosides Research Areas >> Cancer
Target	PKC:30 μM (Ki)
In Vitro	Ingenol is a PKC activator, with a Ki of 30 μM. Ingenol induces ornithine decarboxylase activity (1, 3 mM), and causes morphological changes (1 mM) in primary mouse epidermal keratinocytes. Ingenol (125 μM, 250 μM, 500 μM, 1 mM) also inhibits cell-cell communication[1].
References	[1]. Hasler CM, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8.

Density	1.3±0.1 g/cm3
Boiling Point	523.8±50.0 °C at 760 mmHg
Melting Point	153 °C
Molecular Formula	C₂₀H₂₈O₅
Molecular Weight	348.433
Flash Point	284.7±26.6 °C
Exact Mass	348.193665
PSA	97.99000
LogP	2.95
Vapour Pressure	0.0±3.1 mmHg at 25°C
Index of Refraction	1.625

Ingenol MSDS(Chinese)

Hazard Codes	Xi: Irritant;
Risk Phrases	R38;R41
Safety Phrases	26-36

(1S,4S,5R,6R,9S,10R,12R,14R)-4,5,6-Trihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyltetracyclo[7.5.1.0.0]pentadeca-2,7-dien-15-one

1aa,2a,5b,5ab,6b,8ab,9a,10,10aa-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one

(1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one

1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-

(1aR,2S,5R,5aR,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one

ingenol

MFCD00056380

1alpha,2,5,5alpha,6,9,10,10alpha-Octahydro-5,5alpha,6-trihydroxy-4-hydroxymethyl-1,1,7,9,-retramethyl-1H-2,8alpha-m

1A,2,5,5A,6,9,10,10A OCTAHYDRO-5,5A,6-TRIHYDROXY4(HYDROXYMETHYL)1,1,7,9-TETRAMETHYL1H-2,8 AMETHANOCYCLOPENTA[A]CYCLOPROPA[E]CYCLODECEN-11 ONE

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Ingenol
Price: ￥1178.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Ingenol
Price: $500.0/100mg $950.0/250mg $1900.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: ￥1120/5mg

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Ingenol

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