ROCK2-IN-7

Modify Date: 2024-01-17 15:35:34

ROCK2-IN-7 structure	Common Name	ROCK2-IN-7
	CAS Number	3000541-95-4	Molecular Weight	445.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₈FN₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ROCK2-IN-7

ROCK2-IN-7 is a kinase inhibitor targeting to ROCK2. ROCK2-IN-7 inhibits ROCK2/pSTAT3 Signaling. ROCK2-IN-7 suppresses systemic immunity activation and attenuates inflammation in psoriasis model[1].

Name	ROCK2-IN-7

Description	ROCK2-IN-7 is a kinase inhibitor targeting to ROCK2. ROCK2-IN-7 inhibits ROCK2/pSTAT3 Signaling. ROCK2-IN-7 suppresses systemic immunity activation and attenuates inflammation in psoriasis model[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Signaling Pathways >> Metabolic Enzyme/Protease >> MMP Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> TGF-beta/Smad >> ROCK
Target	ROCK2 MMP-2 Stat-3
References	[1]. Huang, Yun, et al. "Design, Synthesis, and Biological Evaluation of an Orally Bioavailable, Potent, and Selective ROCK2 Inhibitor for Psoriasis Treatment." Journal of Medicinal Chemistry (2023)

Molecular Formula	C₂₆H₂₈FN₅O
Molecular Weight	445.53

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ROCK2-IN-7

Use of ROCK2-IN-7

Names

ROCK2-IN-7 Biological Activity

Chemical & Physical Properties