CCI-006

Modify Date: 2025-08-25 20:21:50

CCI-006 Structure
CCI-006 structure
 Common Name CCI-006
CAS Number 292053-42-0 Molecular Weight 332.33
Density N/A Boiling Point N/A
Molecular Formula C15H12N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CCI-006


CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].

 Names

Name CCI-006
Synonym More Synonyms

 CCI-006 Biological Activity

Description CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].
Related Catalog
Target

Mitochondria[1].

References

[1]. Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.

 Chemical & Physical Properties

Molecular Formula C15H12N2O5S
Molecular Weight 332.33
InChIKey VEXAKEBSBMAIOB-DHZHZOJOSA-N
SMILES COC(=O)C(C#N)=Cc1ccc(-c2ccc(S(N)(=O)=O)cc2)o1

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD01847328
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Chemsrc provides CCI-006(CAS#:292053-42-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of CCI-006 are included as well.>> amp version: CCI-006

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