CCI-006

Modify Date: 2024-01-22 16:07:16

CCI-006 Structure
CCI-006 structure
Common Name CCI-006
CAS Number 292053-42-0 Molecular Weight 332.33
Density N/A Boiling Point N/A
Molecular Formula C15H12N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CCI-006


CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].

 Names

Name CCI-006
Synonym More Synonyms

 CCI-006 Biological Activity

Description CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].
Related Catalog
Target

Mitochondria[1].

References

[1]. Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.

 Chemical & Physical Properties

Molecular Formula C15H12N2O5S
Molecular Weight 332.33

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD01847328