292053-42-0

292053-42-0 structure

Name: CCI-006
Chemical Name: CCI-006
CAS Number: 292053-42-0
Molecular Formula: C₁₅H₁₂N₂O₅S
Molecular Weight: 332.33
Catalog: Signaling Pathways Metabolic Enzyme/Protease Mitochondrial Metabolism
Create Date: 2019-03-30 11:28:34
Modify Date: 2024-01-22 16:07:16
CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].

Name	CCI-006
Synonyms	MFCD01847328

Description	CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism
Target	Mitochondria[1].
References	[1]. Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.

Molecular Formula	C₁₅H₁₂N₂O₅S
Molecular Weight	332.33

Hazard Codes	Xi