1315334-23-6

1315334-23-6 structure

Name: OKI-006
Chemical Name: OKI-006
CAS Number: 1315334-23-6
Molecular Formula: C₂₁H₃₀N₄O₅S₂
Molecular Weight: 482.62
Create Date: 2022-05-21 09:07:33
Modify Date: 2025-08-25 08:00:21
OKI-006 is a potent and orally active inhibitor of histone deacetylase (HDAC). OKI-006 is a unique congener of the natural product HDAC inhibitor largazole. Histone deacetylases (HDACs) play critical roles in epigenomic regulation, and histone acetylation is dysregulated in many human cancers. OKI-006 has the potential for the research of cancer disease[1].

Name	OKI-006

Description	OKI-006 is a potent and orally active inhibitor of histone deacetylase (HDAC). OKI-006 is a unique congener of the natural product HDAC inhibitor largazole. Histone deacetylases (HDACs) play critical roles in epigenomic regulation, and histone acetylation is dysregulated in many human cancers. OKI-006 has the potential for the research of cancer disease[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
References	[1]. Diamond JR, et al. Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors. Mol Cancer Ther. 2022;21(3):397-406.

Molecular Formula	C₂₁H₃₀N₄O₅S₂
Molecular Weight	482.62