CCI-006

Names

[ CAS No. ]:
292053-42-0

[ Name ]:
CCI-006

[Synonym ]:
MFCD01847328

Biological Activity

[Description]:

CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism

[Target]

Mitochondria[1].

[References]

[1]. Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₂N₂O₅S

[ Molecular Weight ]:
332.33

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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