Hydroxy-PEG2-methylamine

Modify Date: 2024-01-22 17:29:34

Hydroxy-PEG2-methylamine Structure
Hydroxy-PEG2-methylamine structure
Common Name Hydroxy-PEG2-methylamine
CAS Number 282551-10-4 Molecular Weight 163.21
Density N/A Boiling Point N/A
Molecular Formula C7H17NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG2-methylamine


PEG3-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG3-methylamine
Synonym More Synonyms

 Hydroxy-PEG2-methylamine Biological Activity

Description PEG3-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C7H17NO3
Molecular Weight 163.21

 Synonyms

MFCD30182052