1835759-76-6
1835759-76-6 structure
- Name: Propargyl-PEG2-methylamine
- Chemical Name: N-Methyl-2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine
- CAS Number: 1835759-76-6
- Molecular Formula: C8H15NO2
- Molecular Weight: 157.210
- Create Date: 2021-01-09 06:12:00
- Modify Date: 2025-09-05 17:35:13
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Propargyl-PEG2-methylamine is a PEG derivative containing a propargyl group and methylamine group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The methylamine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers are useful in the development of antibody drug conjugates.
| Name | N-Methyl-2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine |
|---|---|
| Synonyms |
Ethanamine, N-methyl-2-[2-(2-propyn-1-yloxy)ethoxy]-
MFCD29042339 N-Methyl-2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 214.6±20.0 °C at 760 mmHg |
| Molecular Formula | C8H15NO2 |
| Molecular Weight | 157.210 |
| Flash Point | 83.6±11.2 °C |
| Exact Mass | 157.110275 |
| LogP | -0.16 |
| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
| Index of Refraction | 1.444 |