51951-04-3
51951-04-3 structure
- Name: Hydroxy-PEG2-CH2COOH
- Chemical Name: [2-(2-Hydroxyethoxy)ethoxy]acetic acid
- CAS Number: 51951-04-3
- Molecular Formula: C6H12O5
- Molecular Weight: 164.156
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-20 17:06:44
- Modify Date: 2024-01-20 09:53:33
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Hydroxy-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | [2-(2-Hydroxyethoxy)ethoxy]acetic acid |
|---|---|
| Synonyms |
[2-(2-Hydroxyethoxy)ethoxy]acetic acid
MFCD20640451 Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]- |
| Description | Hydroxy-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.0 g/cm3 |
|---|---|
| Boiling Point | 343.4±0.0 °C at 760 mmHg |
| Molecular Formula | C6H12O5 |
| Molecular Weight | 164.156 |
| Flash Point | 144.3±0.0 °C |
| Exact Mass | 164.068466 |
| LogP | -1.73 |
| Vapour Pressure | 0.0±0.0 mmHg at 25°C |
| Index of Refraction | 1.462 |