6-FLUOROMEVALONATE
6-FLUOROMEVALONATE structure
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Common Name | 6-FLUOROMEVALONATE | ||
|---|---|---|---|---|
| CAS Number | 2822-77-7 | Molecular Weight | 148.132 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 307.8±22.0 °C at 760 mmHg | |
| Molecular Formula | C6H9FO3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 140.0±22.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 6-FLUOROMEVALONATE6-Fluoromevalonate is a mevalonate-pyrophosphate decarboxylase inhibitor. |
| Name | ZR 3516 |
|---|---|
| Synonym | More Synonyms |
| Description | 6-Fluoromevalonate is a mevalonate-pyrophosphate decarboxylase inhibitor. |
|---|---|
| Related Catalog |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 307.8±22.0 °C at 760 mmHg |
| Molecular Formula | C6H9FO3 |
| Molecular Weight | 148.132 |
| Flash Point | 140.0±22.3 °C |
| Exact Mass | 148.053574 |
| LogP | -1.06 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.450 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
| RIDADR | NONH for all modes of transport |
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[Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells].
C. R. Seances. Soc. Biol. Fil. 191(2) , 169-94, (1997) The role of mevalonic acid (MVA) and its products (isoprenoids) in cell proliferation prompted us to investigate the effect of drugs affecting diverse enzymatic steps of the MVA pathway on rat aorta s... |
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Effect of lovastatin and fluoromevalonate on phosphatidylinositol 3-kinase activity stimulated with PDGF.
Clin. Exp. Pharmacol. Physiol. Suppl. 22(1) , S318-20, (1995) 1. Phosphatidylinositol 3-kinase (PI3K) appears to have a crucial role in cellular proliferation induced by platelet-derived growth factor (PDGF). However, the mode of activation of the enzyme has bee... |
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Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS.
Biochim. Biophys. Acta 1811(4) , 227-33, (2011) The isoprenoid biosynthesis pathway provides the cell with a variety of compounds which are involved in multiple cellular processes. Inhibition of this pathway with statins and bisphosphonates is wide... |
| 6-Fluoromevalonate |
| 2H-Pyran-2-one, 4-(fluoromethyl)tetrahydro-4-hydroxy- |
| ZR 3516 |
| MFCD08276919 |
| 4-(fluoromethyl)tetrahydro-4-hydroxy-2h-pyran-2-one |
| Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one |
| 4-(Fluoromethyl)-4-hydroxytetrahydro-2H-pyran-2-one |
| 4-(fluoromethyl)-4-hydroxy-2-oxanone |