NLRP3-IN-11
Modify Date: 2025-09-07 16:05:17
NLRP3-IN-11 structure
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Common Name | NLRP3-IN-11 | ||
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| CAS Number | 2769040-91-5 | Molecular Weight | 344.80 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H17ClN4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NLRP3-IN-11NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of ＜0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1]. |
| Name | NLRP3-IN-11 |
|---|
| Description | NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of ＜0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1]. |
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| Related Catalog | |
| Target |
NLRP3:<0.3 μM (IC50) |
| In Vitro | NLRP3-IN-11 has biological activity with an IC50 value of ＜0.3 μM in human PBMC NLRP3 assay[1] |
| References |
[1]. HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1. |
| Molecular Formula | C17H17ClN4O2 |
|---|---|
| Molecular Weight | 344.80 |
| InChIKey | UDNICEVHCYUJFU-UHFFFAOYSA-N |
| SMILES | CC(C)(O)CNc1nnc(-c2ccc(Cl)cc2O)c2ccncc12 |