NLRP3-IN-3 structure
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Common Name | NLRP3-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2254433-37-7 | Molecular Weight | 439.534 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H25N5O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NLRP3-IN-3NLRP3-IN-3 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 1.26 nM in THP1 cells, showing good pharmacokinetic profiles with oral bioavailability. |
| Name | NLRP3-IN-3 |
|---|
| Description | NLRP3-IN-3 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 1.26 nM in THP1 cells, showing good pharmacokinetic profiles with oral bioavailability. |
|---|---|
| References | 1. Sharma R., Iyer P., Agarwal S. Novel Substituted Sulfoximine Compounds. WO/2018/225018. |
| Molecular Formula | C22H25N5O3S |
|---|---|
| Molecular Weight | 439.534 |