PD-1/PD-L1-IN-25
Modify Date: 2024-01-20 21:01:20
PD-1/PD-L1-IN-25 structure
|
Common Name | PD-1/PD-L1-IN-25 | ||
|---|---|---|---|---|
| CAS Number | 2768759-52-8 | Molecular Weight | 493.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H24ClN3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PD-1/PD-L1-IN-25PD-1/PD-L1-IN-25 (compound D2) is an inhibitor of PD-1/PD-L1 interaction with an IC50 value of 16.17 nM. PD-1/PD-L1-IN-25 activates the antitumor immunity of T cells efficiently in PBMCs. PD-1/PD-L1-IN-25 can be used for the research of cancer[1]. |
| Name | PD-1/PD-L1-IN-25 |
|---|
| Description | PD-1/PD-L1-IN-25 (compound D2) is an inhibitor of PD-1/PD-L1 interaction with an IC50 value of 16.17 nM. PD-1/PD-L1-IN-25 activates the antitumor immunity of T cells efficiently in PBMCs. PD-1/PD-L1-IN-25 can be used for the research of cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 16.17 nM (PD-1/PD-L1)[1]. |
| In Vitro | PD-1/PD-L1-IN-25 (0-1 μM; 90 min) inhibits PD-1/PD-L1 interaction with an IC50 value of 16.17 nM[1]. PD-1/PD-L1-IN-25 (0-2 μM; 2 h) activates the antitumor immunity of T cells efficiently in PBMCs[1]. Cell Cytotoxicity Assay[1] Cell Line: MDA-MB 231 cells by human PBMCs Concentration: 0-2 μM Incubation Time: 2 hours Result: Showed no toxicity towards MDA-MB 231 cells, and activated the antitumor immunity of PBMCs to kill MDA-MB 231 cells efficiently at a concentration of 1.0 μM. |
| References |
| Molecular Formula | C26H24ClN3O5 |
|---|---|
| Molecular Weight | 493.94 |