DHFR-IN-1
Modify Date: 2025-09-26 21:50:39
DHFR-IN-1 structure
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Common Name | DHFR-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2757991-65-2 | Molecular Weight | 498.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H22N6O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DHFR-IN-1DHFR-IN-1 (compound 12) is a potent and selective DHFR (dihydrofolate reductase)inhibitor, with an IC50 of 40.71 nM. DHFR-IN-1 exhibits promising antibacterial activity against gram-positive and gram-negative bacteria. DHFR-IN-1 exhibits moderate antifungal activities. DHFR-IN-1 exhibits a high synergistic effect with Levofloxacin (HY-B0330), where the FIC (fractional inhibitory concentration index) value is 0.249[1]. |
| Name | DHFR-IN-1 |
|---|
| Description | DHFR-IN-1 (compound 12) is a potent and selective DHFR (dihydrofolate reductase)inhibitor, with an IC50 of 40.71 nM. DHFR-IN-1 exhibits promising antibacterial activity against gram-positive and gram-negative bacteria. DHFR-IN-1 exhibits moderate antifungal activities. DHFR-IN-1 exhibits a high synergistic effect with Levofloxacin (HY-B0330), where the FIC (fractional inhibitory concentration index) value is 0.249[1]. |
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| Related Catalog | |
| Target |
IC50: 40.71 ± 1.86 nM (DHFR)[1] |
| References |
| Molecular Formula | C22H22N6O4S2 |
|---|---|
| Molecular Weight | 498.58 |