Cbz-PEG5-Br

Modify Date: 2024-01-12 00:06:44

Cbz-PEG5-Br Structure
Cbz-PEG5-Br structure
Common Name Cbz-PEG5-Br
CAS Number 2710803-69-1 Molecular Weight 478.37
Density N/A Boiling Point N/A
Molecular Formula C20H32BrNO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cbz-PEG5-Br


Cbz-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Cbz-PEG5-Br

 Cbz-PEG5-Br Biological Activity

Description Cbz-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C20H32BrNO7
Molecular Weight 478.37
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