Propargyl-PEG5-Br

Modify Date: 2024-01-09 12:15:10

Propargyl-PEG5-Br Structure
Propargyl-PEG5-Br structure
Common Name Propargyl-PEG5-Br
CAS Number 1287660-83-6 Molecular Weight 339.22
Density N/A Boiling Point N/A
Molecular Formula C13H23BrO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG5-Br


Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG5-Br
Synonym More Synonyms

 Propargyl-PEG5-Br Biological Activity

Description Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1009.

 Chemical & Physical Properties

Molecular Formula C13H23BrO5
Molecular Weight 339.22

 Synonyms

MFCD32263750
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