alpha-Hederin
Modify Date: 2024-01-02 12:18:53
alpha-Hederin structure
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Common Name | alpha-Hederin | ||
|---|---|---|---|---|
| CAS Number | 27013-91-8 | Molecular Weight | 750.956 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 849.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C41H66O12 | Melting Point | 215ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 250.7±27.8 °C | |
Use of alpha-Hederinalpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation，In vitro: a-hederin is cytotoxic and inhibits proliferation in bothcel lines at rather low concentrations. , a-hederin reduces themitotic activity in treated cels.[1]In vivo: alpha-hederin had preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses. [2] |
| Name | kalopanaxsaponin A |
|---|---|
| Synonym | More Synonyms |
| Description | alpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation，In vitro: a-hederin is cytotoxic and inhibits proliferation in bothcel lines at rather low concentrations. , a-hederin reduces themitotic activity in treated cels.[1]In vivo: alpha-hederin had preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses. [2] |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 849.6±65.0 °C at 760 mmHg |
| Melting Point | 215ºC (dec.) |
| Molecular Formula | C41H66O12 |
| Molecular Weight | 750.956 |
| Flash Point | 250.7±27.8 °C |
| Exact Mass | 750.455444 |
| PSA | 195.60000 |
| LogP | 8.37 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.601 |
| Storage condition | 2~8℃ |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Hazard Codes | Xi |
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| Risk Phrases | 22 |
| Safety Phrases | 22-45-24/25 |
| RIDADR | UN 1544 |
| RTECS | RK0177800 |
| Precursor 8 | |
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| DownStream 4 | |
CAS#:14216-03-6
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Induction of highly curved structures in relation to membrane permeabilization and budding by the triterpenoid saponins, α- and δ-Hederin.
J. Biol. Chem. 288(20) , 14000-17, (2013) The interactions of triterpenoid monodesmosidic saponins, α-hederin and δ-hederin, with lipid membranes are involved in their permeabilizing effect. Unfortunately, the interactions of these saponins w... |
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Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors.
Biochemistry 48(15) , 3477-82, (2009) Hederacoside C, alpha-hederin, and hederagenin are saponins of dry extracts obtained from the leaves of ivy (Hedera helix L.). Internalization of beta(2)-adrenergic receptor-GFP fusion proteins after ... |
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Participation of cholinergic pathways in α-hederin-induced contraction of rat isolated stomach strips.
Phytomedicine 19(7) , 591-5, (2012) The dry extract of Hedra helix leaves and its main active compounds, predominantly α-hederin and hederacoside C, has been traditionally believed to act spasmolytic. However, it has been recently prove... |
| α-Hederin |
| (3β)-3-{[2-O-(6-Deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}-23-hydroxyolean-12-en-28-oic acid |
| Alpha-hederin |
| glycosidel-e1 |
| Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-, (3β)- |
| UNII:4H15F0GLV2 |
| sapindosidea |
| HELIXIN |
| nepalin2 |
| dipsacobioside |
| Hederoside B |
| koronaroside A |
| hederosidec |
| akebosidestc |
| taurosidee |
| A-HEDERIN |
| SAPINDOSIDE A |
| HEDERIN |
| Hederin, α- |
| alpha-Hederin |
- BioBioPha
- China
- Product Name: alpha-Hederin
- Price: ￥Inquiry/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: alpha-Hederin
- Price: ￥1178.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: alpha-Hederin
- Price: $300.0/100mg $600.0/250mg $1200.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: alpha-Hederine
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: discount ALPHA-HEDERIN
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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