B-Raf IN 5

Modify Date: 2024-01-12 17:56:05

B-Raf IN 5 Structure
B-Raf IN 5 structure
Common Name B-Raf IN 5
CAS Number 2648698-30-8 Molecular Weight 583.01
Density N/A Boiling Point N/A
Molecular Formula C23H18ClF3N6O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of B-Raf IN 5


B-Raf IN 5 (compound 3b) is a potent inhibitor of protein kinase B-Raf with an IC50 of 2.0 nM. B-Raf IN 5 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].

 Names

Name B-Raf IN 5

 B-Raf IN 5 Biological Activity

Description B-Raf IN 5 (compound 3b) is a potent inhibitor of protein kinase B-Raf with an IC50 of 2.0 nM. B-Raf IN 5 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].
Related Catalog
References

[1]. Schneider M, et al. Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding. J Med Chem. 2022;65(2):1552-1566.

 Chemical & Physical Properties

Molecular Formula C23H18ClF3N6O3S2
Molecular Weight 583.01
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: B-Raf IN 5
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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