B-Raf IN 7

Modify Date: 2025-08-27 14:10:54

B-Raf IN 7 structure	Common Name	B-Raf IN 7
	CAS Number	2477725-07-6	Molecular Weight	328.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₆N₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of B-Raf IN 7

B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor, with an IC50 of 110.23 nM. B-Raf IN 7 exhibits antitumor activity against colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela) and human prostate cancer (PC-3) cells, with IC50 values of 7.50, 9.87, 10.57, 11.63 and 12.83 µM[1].

Name	B-Raf IN 7

Description	B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor, with an IC50 of 110.23 nM. B-Raf IN 7 exhibits antitumor activity against colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela) and human prostate cancer (PC-3) cells, with IC50 values of 7.50, 9.87, 10.57, 11.63 and 12.83 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	B-Raf:110.23 ± 0 nM (IC50)
References	[1]. Thabit MG, et al. Design, synthesis and molecular modeling of phenyl dihydropyridazinone derivatives as B-Raf inhibitors with anticancer activity. Bioorg Chem. 2020 Oct;103:104148.

Molecular Formula	C₁₅H₁₆N₆O₃
Molecular Weight	328.33

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

B-Raf IN 7

Use of B-Raf IN 7

Names

B-Raf IN 7 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.