2648698-34-2

2648698-34-2 structure

Name: B-Raf IN 6
Chemical Name: B-Raf IN 6
CAS Number: 2648698-34-2
Molecular Formula: C₂₄H₂₁F₃N₆O₂S₂
Molecular Weight: 546.59
Catalog: Signaling Pathways MAPK/ERK Pathway Raf
Create Date: 2022-04-06 22:34:16
Modify Date: 2024-01-10 11:48:35
B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].

Name	B-Raf IN 6

Description	B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
References	[1]. Schneider M, et al. Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding. J Med Chem. 2022;65(2):1552-1566.

Molecular Formula	C₂₄H₂₁F₃N₆O₂S₂
Molecular Weight	546.59