ROCK-IN-9
Modify Date: 2024-01-02 18:53:28
ROCK-IN-9 structure
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Common Name | ROCK-IN-9 | ||
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| CAS Number | 2643334-76-1 | Molecular Weight | 381.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H20FN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ROCK-IN-9ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1]. |
| Name | ROCK-IN-9 |
|---|
| Description | ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1]. |
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| Related Catalog | |
| References |
[1]. Li, Jinping, et al. Rock inhibitor, preparation method therefor and use thereof. WO2021093795. |
| Molecular Formula | C20H20FN5O2 |
|---|---|
| Molecular Weight | 381.40 |