2643334-76-1
2643334-76-1 structure
- Name: ROCK-IN-9
- Chemical Name: ROCK-IN-9
- CAS Number: 2643334-76-1
- Molecular Formula: C20H20FN5O2
- Molecular Weight: 381.40
- Catalog: Signaling Pathways Cell Cycle/DNA Damage ROCK
- Create Date: 2023-10-23 14:58:26
- Modify Date: 2025-08-26 17:59:02
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ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1].
| Name | ROCK-IN-9 |
|---|
| Description | ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1]. |
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| Related Catalog | |
| References |
[1]. Li, Jinping, et al. Rock inhibitor, preparation method therefor and use thereof. WO2021093795. |
| Molecular Formula | C20H20FN5O2 |
|---|---|
| Molecular Weight | 381.40 |