FTO-IN-8
Modify Date: 2025-11-26 09:18:22
FTO-IN-8 structure
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Common Name | FTO-IN-8 | ||
|---|---|---|---|---|
| CAS Number | 2640366-38-5 | Molecular Weight | 346.85 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H23ClN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FTO-IN-8FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase (FTO) (fat mass- and obesity-associated protein) inhibitor with the IC50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity[1]. |
| Name | FTO-IN-8 |
|---|
| Description | FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase (FTO) (fat mass- and obesity-associated protein) inhibitor with the IC50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | FTO-IN-8 (FTO-43) (0-50 μM, 24-72 h) inhibits the proliferation of cancer cells with no cytotoxicity to normal colonic cells[1]. FTO-IN-8 (FTO-43) can increase m 6 A and m 6 A m levels and inhibits Wnt/PI3K-Akt signaling in gastric cancer AGS cells[1]. Cell Viability Assay[1] Cell Line: AGS, SNU16, and KATOIII cell lines Concentration: 0-50 μM Incubation Time: 24, 48, 72 hours Result: Inhibited the growth of SNU16, KATOIII and AGS with the EC50 values of 17.7 μM, 35.9 μM and 20.3 μM, respectively. |
| References |
| Molecular Formula | C19H23ClN2O2 |
|---|---|
| Molecular Weight | 346.85 |
| InChIKey | QHNARTNMADDQGU-UHFFFAOYSA-N |
| SMILES | Clc1ccccc1-c1ccc(CNCC2(N3CCCC3)COC2)o1 |