SOS1-IN-8

Modify Date: 2025-08-27 19:57:31

SOS1-IN-8 Structure
SOS1-IN-8 structure
Common Name SOS1-IN-8
CAS Number 2759387-92-1 Molecular Weight 477.48
Density N/A Boiling Point N/A
Molecular Formula C24H26F3N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SOS1-IN-8


SOS1-IN-8 is a potent SOS1 inhibitor with IC50s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2)[1].

 Names

Name SOS1-IN-8

 SOS1-IN-8 Biological Activity

Description SOS1-IN-8 is a potent SOS1 inhibitor with IC50s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2)[1].
Related Catalog
Target

SOS1-G12D:11.6 nM (IC50)

SOS1-G12V:40.7 nM (IC50)

References

[1]. Fused pyridazine derivative, preparation method therefor and pharmaceutical use thereof. WO2022017339A1.

 Chemical & Physical Properties

Molecular Formula C24H26F3N3O4
Molecular Weight 477.48
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