2759387-92-1

2759387-92-1 structure
2759387-92-1 structure
  • Name: SOS1-IN-8
  • Chemical Name: SOS1-IN-8
  • CAS Number: 2759387-92-1
  • Molecular Formula: C24H26F3N3O4
  • Molecular Weight: 477.48
  • Catalog: Signaling Pathways GPCR/G Protein Ras
  • Create Date: 2022-04-10 13:23:45
  • Modify Date: 2025-08-27 19:57:31
  • SOS1-IN-8 is a potent SOS1 inhibitor with IC50s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2)[1].

Name SOS1-IN-8
Description SOS1-IN-8 is a potent SOS1 inhibitor with IC50s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2)[1].
Related Catalog
Target

SOS1-G12D:11.6 nM (IC50)

SOS1-G12V:40.7 nM (IC50)

References

[1]. Fused pyridazine derivative, preparation method therefor and pharmaceutical use thereof. WO2022017339A1.

Molecular Formula C24H26F3N3O4
Molecular Weight 477.48
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