IKK2-IN-8

Modify Date: 2025-08-25 21:21:59

IKK2-IN-8 Structure
IKK2-IN-8 structure
Common Name IKK2-IN-8
CAS Number 1266240-87-2 Molecular Weight 380.47
Density N/A Boiling Point N/A
Molecular Formula C19H20N6OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IKK2-IN-8


IKK2-IN-8 is a potent, selective IKK2 inhibitor with IC50 of 6 nM, displays >40-fold selectivity over IKK1 (IC50=230 nM); inhibits lipopolysaccharide (LPS) induced TNFα production in human PBMCs with IC50 of 80 nM.

 Names

Name IKK2-IN-8

 IKK2-IN-8 Biological Activity

Description IKK2-IN-8 is a potent, selective IKK2 inhibitor with IC50 of 6 nM, displays >40-fold selectivity over IKK1 (IC50=230 nM); inhibits lipopolysaccharide (LPS) induced TNFα production in human PBMCs with IC50 of 80 nM.
References References 1. Dyckman AJ, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):383-6. View Related Products by Target IκB kinase (IKK)

 Chemical & Physical Properties

Molecular Formula C19H20N6OS
Molecular Weight 380.47
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