ASPER-29

Modify Date: 2025-09-21 00:41:31

ASPER-29 Structure
ASPER-29 structure
Common Name ASPER-29
CAS Number 2630388-03-1 Molecular Weight 621.54
Density N/A Boiling Point N/A
Molecular Formula C31H29BrN2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ASPER-29


ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer[1].

 Names

Name ASPER-29

 ASPER-29 Biological Activity

Description ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer[1].
Related Catalog
Target

cathepsin L:6.03 μM (IC50)

cathepsin S:5.02 μM (IC50)

In Vitro ASPER-29 具有双重 Cat L 和 S 抑制效力,IC50 值分别为 6.03 μM 和 5.02 μM[1]。 ASPER-29 对胰腺癌 BxPC-3 和 PANC-1 细胞显示出明确的抗转移作用[1]。
References

[1]. Haoqiang Huang, et al. Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells. Bioorg Med Chem Lett. 2022 Nov 23;80:129087.  

 Chemical & Physical Properties

Molecular Formula C31H29BrN2O5S
Molecular Weight 621.54
InChIKey PVSAZGHLDWSSJJ-PXJZQJOASA-N
SMILES O=C(NC(Cc1ccccc1)C(=O)OCC(Cc1ccccc1)NS(=O)(=O)c1ccc(Br)cc1)c1ccccc1
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