2630388-03-1

2630388-03-1 structure

Name: ASPER-29
Chemical Name: ASPER-29
CAS Number: 2630388-03-1
Molecular Formula: C₃₁H₂₉BrN₂O₅S
Molecular Weight: 621.54
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cathepsin
Create Date: 2023-04-03 18:13:05
Modify Date: 2024-09-16 10:09:00
ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer[1].

Name	ASPER-29

Description	ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	cathepsin L:6.03 μM (IC50) cathepsin S:5.02 μM (IC50)
In Vitro	ASPER-29 具有双重 Cat L 和 S 抑制效力，IC50 值分别为 6.03 μM 和 5.02 μM[1]。 ASPER-29 对胰腺癌 BxPC-3 和 PANC-1 细胞显示出明确的抗转移作用[1]。
References	[1]. Haoqiang Huang, et al. Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells. Bioorg Med Chem Lett. 2022 Nov 23;80:129087.

Molecular Formula	C₃₁H₂₉BrN₂O₅S
Molecular Weight	621.54