Artemisiane E

Modify Date: 2024-04-03 19:17:32

Artemisiane E Structure
Artemisiane E structure
 Common Name Artemisiane E
CAS Number 2618700-77-7 Molecular Weight 342.39
Density N/A Boiling Point N/A
Molecular Formula C20H22O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Artemisiane E


Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1].

 Names

Name Artemisiane E

 Artemisiane E Biological Activity

Description Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1].
Related Catalog
Target

IC50: 8.9 μM (PI3K/AKT pathway)[1]

In Vitro Artemisiane E (Compound 8) (25 and 50 μM) inhibits AKT activity in MM121224 cells[1].
References

[1]. Dürr L, et al. A Dimerosesquiterpene and Sesquiterpene Lactones from Artemisia argyi Inhibiting Oncogenic PI3K/AKT Signaling in Melanoma Cells. J Nat Prod. 2022 Nov 25;85(11):2557-2569.  

 Chemical & Physical Properties

Molecular Formula C20H22O5
Molecular Weight 342.39
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