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2618700-77-7

2618700-77-7 structure

2618700-77-7 structure

Name: Artemisiane E
Chemical Name: Artemisiane E
CAS Number: 2618700-77-7
Molecular Formula: C₂₀H₂₂O₅
Molecular Weight: 342.39
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2023-03-03 12:34:22
Modify Date: 2024-04-03 19:17:32
Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1].

Name	Artemisiane E

Description	Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Target	IC50: 8.9 μM (PI3K/AKT pathway)[1]
In Vitro	Artemisiane E (Compound 8) (25 and 50 μM) inhibits AKT activity in MM121224 cells[1].
References	[1]. Dürr L, et al. A Dimerosesquiterpene and Sesquiterpene Lactones from Artemisia argyi Inhibiting Oncogenic PI3K/AKT Signaling in Melanoma Cells. J Nat Prod. 2022 Nov 25;85(11):2557-2569.

Molecular Formula	C₂₀H₂₂O₅
Molecular Weight	342.39

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