Pan-Trk-IN-2

Modify Date: 2025-08-25 07:50:00

Pan-Trk-IN-2 structure	Common Name	Pan-Trk-IN-2
	CAS Number	2583778-77-0	Molecular Weight	506.86
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₈ClF₃N₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pan-Trk-IN-2

Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity[1].

Name	Pan-Trk-IN-2

Description	Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor
References	[1]. Pan S,et al. Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants. J Med Chem. 2022 Feb 10;65(3):2035-2058.

Molecular Formula	C₂₂H₁₈ClF₃N₆O₃
Molecular Weight	506.86
InChIKey	KQZFHDUZMBMCMO-UHFFFAOYSA-N
SMILES	CC1(C)Oc2c(ncnc2Nc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)NC1=O

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