hMAO-B-IN-3

Modify Date: 2024-01-16 10:37:59

hMAO-B-IN-3 Structure
hMAO-B-IN-3 structure
Common Name hMAO-B-IN-3
CAS Number 2581113-51-9 Molecular Weight 333.34
Density N/A Boiling Point N/A
Molecular Formula C20H15NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hMAO-B-IN-3


hMAO-B-IN-3 (Compound 15) is a potent inhibitor of hMAO-B with an IC50 of 47.4 nM. hMAO-B-IN-3 is playing favourable drug-like properties and a broad safety window. hMAO-B-IN-3 is thus a suitable candidate for lead optimization and the development of multitarget-directed ligands[1].

 Names

Name hMAO-B-IN-3

 hMAO-B-IN-3 Biological Activity

Description hMAO-B-IN-3 (Compound 15) is a potent inhibitor of hMAO-B with an IC50 of 47.4 nM. hMAO-B-IN-3 is playing favourable drug-like properties and a broad safety window. hMAO-B-IN-3 is thus a suitable candidate for lead optimization and the development of multitarget-directed ligands[1].
Related Catalog
References

[1]. Chavarria D, et al. Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies. Eur J Med Chem. 2020 Jan 1;185:111770.

 Chemical & Physical Properties

Molecular Formula C20H15NO4
Molecular Weight 333.34