2573775-59-2
2573775-59-2 structure
- Name: Cbl-b-IN-3
- Chemical Name: Cbl-b-IN-3
- CAS Number: 2573775-59-2
- Molecular Formula: C30H34F3N5O
- Molecular Weight: 537.62
- Catalog: Signaling Pathways Metabolic Enzyme/Protease E1/E2/E3 Enzyme
- Create Date: 2022-09-01 07:59:18
- Modify Date: 2024-08-29 19:51:45
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Cbl-b-IN-3 (Compound 23) is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation[1].
| Name | Cbl-b-IN-3 |
|---|
| Description | Cbl-b-IN-3 (Compound 23) is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation[1]. |
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| Related Catalog | |
| Target |
IC50: < 1 nM (Cbl-b)[1] |
| In Vitro | Cbl-b-IN-3 (Compound 23) enhances IL-2 secretion by T-cells stimulated with an anti-CD3 antibody alone or in combination with an anti-CD28 antibody[1]. |
| References |
| Molecular Formula | C30H34F3N5O |
|---|---|
| Molecular Weight | 537.62 |