Cbl-b-IN-3
Modify Date: 2024-08-29 19:51:45
Cbl-b-IN-3 structure
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Common Name | Cbl-b-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2573775-59-2 | Molecular Weight | 537.62 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H34F3N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Cbl-b-IN-3Cbl-b-IN-3 (Compound 23) is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation[1]. |
| Name | Cbl-b-IN-3 |
|---|
| Description | Cbl-b-IN-3 (Compound 23) is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation[1]. |
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| Related Catalog | |
| Target |
IC50: < 1 nM (Cbl-b)[1] |
| In Vitro | Cbl-b-IN-3 (Compound 23) enhances IL-2 secretion by T-cells stimulated with an anti-CD3 antibody alone or in combination with an anti-CD28 antibody[1]. |
| References |
| Molecular Formula | C30H34F3N5O |
|---|---|
| Molecular Weight | 537.62 |